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WNT-activated bone grafts repair osteonecrotic lesions in aged animals

The Wnt pathway is a new target in bone therapeutic space. WNT proteins are potent stem cell activators and pro-osteogenic agents. Here, we gained insights into the molecular and cellular mechanisms responsible for liposome-reconstituted recombinant human WNT3A protein (L-WNT3A) efficacy to treat os...

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Detalles Bibliográficos
Autores principales:	Salmon, B., Liu, B., Shen, E., Chen, T., Li, J., Gillette, M., Ransom, R. C., Ezran, M., Johnson, C. A., Castillo, A. B., Shen, W. J., Kraemer, F. B., Smith, A. A., Helms, J. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660190/ https://www.ncbi.nlm.nih.gov/pubmed/29079746 http://dx.doi.org/10.1038/s41598-017-14395-9

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