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Ocular antigen does not cause disease unless presented in the context of inflammation
Ocular antigens are sequestered behind the blood-retina barrier and the ocular environment protects ocular tissues from autoimmune attack. The signals required to activate autoreactive T cells and allow them to cause disease in the eye remain in part unclear. In particular, the consequences of perip...
Autores principales: | Voigt, Valentina, Wikstrom, Matthew E., Kezic, Jelena M., Schuster, Iona S., Fleming, Peter, Makinen, Kimmo, Daley, Stephen R., Andoniou, Christopher E., Degli-Esposti, Mariapia A., Forrester, John V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660195/ https://www.ncbi.nlm.nih.gov/pubmed/29079770 http://dx.doi.org/10.1038/s41598-017-14618-z |
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