MMP proteolytic activity regulates cancer invasiveness by modulating integrins

Cancer invasion through dense extracellular matrices (ECMs) is mediated by matrix metalloproteinases (MMPs) which degrade the ECM thereby creating paths for migration. However, how this degradation influences the phenotype of cancer cells is not fully clear. Here we address this question by probing...

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Detalles Bibliográficos
Autores principales: Das, Alakesh, Monteiro, Melissa, Barai, Amlan, Kumar, Sandeep, Sen, Shamik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660204/
https://www.ncbi.nlm.nih.gov/pubmed/29079818
http://dx.doi.org/10.1038/s41598-017-14340-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660204/
https://www.ncbi.nlm.nih.gov/pubmed/29079818
http://dx.doi.org/10.1038/s41598-017-14340-w

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