Cargando…
MMP proteolytic activity regulates cancer invasiveness by modulating integrins
Cancer invasion through dense extracellular matrices (ECMs) is mediated by matrix metalloproteinases (MMPs) which degrade the ECM thereby creating paths for migration. However, how this degradation influences the phenotype of cancer cells is not fully clear. Here we address this question by probing...
Autores principales: | Das, Alakesh, Monteiro, Melissa, Barai, Amlan, Kumar, Sandeep, Sen, Shamik |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660204/ https://www.ncbi.nlm.nih.gov/pubmed/29079818 http://dx.doi.org/10.1038/s41598-017-14340-w |
Ejemplares similares
-
Measuring microenvironment-tuned nuclear stiffness of cancer cells with atomic force microscopy
por: Barai, Amlan, et al.
Publicado: (2021) -
Proteolytic and non-proteolytic regulation of collective cell invasion: tuning by ECM density and organization
por: Kumar, Sandeep, et al.
Publicado: (2016) -
Multicompartment cell-based modeling of confined migration: regulation by cell intrinsic and extrinsic factors
por: Kumar, Sandeep, et al.
Publicado: (2018) -
Amoebal Tubulin Cleavage Late during Infection Is a Characteristic Feature of Mimivirus but Not of Marseillevirus
por: Goyal, Nisha, et al.
Publicado: (2022) -
Blockade of Rho-associated protein kinase (ROCK) inhibits the contractility and invasion potential of cancer stem like cells
por: Srinivasan, Srisathya, et al.
Publicado: (2017)