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Depletion of Mageb16 induces differentiation of pluripotent stem cells predominantly into mesodermal derivatives
The Melanoma-associated Antigen gene family (MAGE) generally encodes for tumour antigens. We had identified that one of the MAGE gene members, Mageb16 was highly expressed in undifferentiated murine embryonic stem cells (ESCs). While the role of Mageb16 in stemness and differentiation of pluripotent...
Autores principales: | Gaspar, John Antonydas, Srinivasan, Sureshkumar Perumal, Sureshkumar, Poornima, Doss, Michael Xavier, Hescheler, Jürgen, Papadopoulos, Symeon, Sachinidis, Agapios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660239/ https://www.ncbi.nlm.nih.gov/pubmed/29079788 http://dx.doi.org/10.1038/s41598-017-14561-z |
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