Norrin protects optic nerve axons from degeneration in a mouse model of glaucoma

Norrin is a secreted signaling molecule activating the Wnt/β-catenin pathway. Since Norrin protects retinal neurons from experimental acute injury, we were interested to learn if Norrin attenuates chronic damage of retinal ganglion cells (RGC) and their axons in a mouse model of glaucoma. Transgenic...

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Detalles Bibliográficos
Autores principales: Leopold, Stephanie A., Zeilbeck, Ludwig F., Weber, Gregor, Seitz, Roswitha, Bösl, Michael R., Jägle, Herbert, Fuchshofer, Rudolf, Tamm, Ernst R., Ohlmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660254/
https://www.ncbi.nlm.nih.gov/pubmed/29079753
http://dx.doi.org/10.1038/s41598-017-14423-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660254/
https://www.ncbi.nlm.nih.gov/pubmed/29079753
http://dx.doi.org/10.1038/s41598-017-14423-8

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