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Binding and Signaling Studies Disclose a Potential Allosteric Site for Cannabidiol in Cannabinoid CB(2) Receptors

The mechanism of action of cannabidiol (CBD), the main non-psychotropic component of Cannabis sativa L., is not completely understood. First assumed that the compound was acting via cannabinoid CB(2) receptors (CB(2)Rs) it is now suggested that it interacts with non-cannabinoid G-protein-coupled rec...

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Detalles Bibliográficos
Autores principales: Martínez-Pinilla, Eva, Varani, Katia, Reyes-Resina, Irene, Angelats, Edgar, Vincenzi, Fabrizio, Ferreiro-Vera, Carlos, Oyarzabal, Julen, Canela, Enric I., Lanciego, José L., Nadal, Xavier, Navarro, Gemma, Borea, Pier Andrea, Franco, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660261/
https://www.ncbi.nlm.nih.gov/pubmed/29109685
http://dx.doi.org/10.3389/fphar.2017.00744

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