Cargando…
Binding and Signaling Studies Disclose a Potential Allosteric Site for Cannabidiol in Cannabinoid CB(2) Receptors
The mechanism of action of cannabidiol (CBD), the main non-psychotropic component of Cannabis sativa L., is not completely understood. First assumed that the compound was acting via cannabinoid CB(2) receptors (CB(2)Rs) it is now suggested that it interacts with non-cannabinoid G-protein-coupled rec...
Autores principales: | Martínez-Pinilla, Eva, Varani, Katia, Reyes-Resina, Irene, Angelats, Edgar, Vincenzi, Fabrizio, Ferreiro-Vera, Carlos, Oyarzabal, Julen, Canela, Enric I., Lanciego, José L., Nadal, Xavier, Navarro, Gemma, Borea, Pier Andrea, Franco, Rafael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660261/ https://www.ncbi.nlm.nih.gov/pubmed/29109685 http://dx.doi.org/10.3389/fphar.2017.00744 |
Ejemplares similares
-
Cannabigerol Action at Cannabinoid CB(1) and CB(2) Receptors and at CB(1)–CB(2) Heteroreceptor Complexes
por: Navarro, Gemma, et al.
Publicado: (2018) -
Update on the recent development of allosteric modulators for adenosine receptors and their therapeutic applications
por: Pasquini, Silvia, et al.
Publicado: (2022) -
A(1) Adenosine Receptor Partial Agonists and Allosteric Modulators: Advancing Toward the Clinic?
por: Vincenzi, Fabrizio, et al.
Publicado: (2020) -
Allosteric Modulation of the CB1 Cannabinoid Receptor by Cannabidiol—A Molecular Modeling Study of the N-Terminal Domain and the Allosteric-Orthosteric Coupling
por: Jakowiecki, Jakub, et al.
Publicado: (2021) -
Anxiolytic properties of A(1) adenosine receptor PAMs
por: Vincenzi, Fabrizio, et al.
Publicado: (2016)