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Localization of Double-Strand Break Repair Proteins to Viral Replication Compartments following Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus

Double-strand breaks (DSBs) in DNA are recognized by the Ku70/80 heterodimer and the MRE11-RAD50-NBS1 (MRN) complex and result in activation of the DNA-PK and ATM kinases, which play key roles in regulating the cellular DNA damage response (DDR). DNA tumor viruses such as Kaposi's sarcoma-assoc...

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Detalles Bibliográficos
Autores principales:	Hollingworth, Robert, Horniblow, Richard D., Forrest, Calum, Stewart, Grant S., Grand, Roger J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660498/ https://www.ncbi.nlm.nih.gov/pubmed/28855246 http://dx.doi.org/10.1128/JVI.00930-17

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