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Dexamethasone and Monophosphoryl Lipid A Induce a Distinctive Profile on Monocyte-Derived Dendritic Cells through Transcriptional Modulation of Genes Associated With Essential Processes of the Immune Response
There is growing interest in the use of tolerogenic dendritic cells (tolDCs) as a potential target for immunotherapy. However, the molecular bases that drive the differentiation of monocyte-derived DCs (moDCs) toward a tolerogenic state are still poorly understood. Here, we studied the transcription...
Autores principales: | García-González, Paulina A., Schinnerling, Katina, Sepúlveda-Gutiérrez, Alejandro, Maggi, Jaxaira, Mehdi, Ahmed M., Nel, Hendrik J., Pesce, Bárbara, Larrondo, Milton L., Aravena, Octavio, Molina, María C., Catalán, Diego, Thomas, Ranjeny, Verdugo, Ricardo A., Aguillón, Juan C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660598/ https://www.ncbi.nlm.nih.gov/pubmed/29109727 http://dx.doi.org/10.3389/fimmu.2017.01350 |
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