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Widespread Post-transcriptional Attenuation of Genomic Copy-Number Variation in Cancer

Copy-number variations (CNVs) are ubiquitous in cancer and often act as driver events, but the effects of CNVs on the proteome of tumors are poorly understood. Here, we analyze recently published genomics, transcriptomics, and proteomics datasets made available by CPTAC and TCGA consortia on 282 bre...

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Detalles Bibliográficos
Autores principales:	Gonçalves, Emanuel, Fragoulis, Athanassios, Garcia-Alonso, Luz, Cramer, Thorsten, Saez-Rodriguez, Julio, Beltrao, Pedro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660600/ https://www.ncbi.nlm.nih.gov/pubmed/29032074 http://dx.doi.org/10.1016/j.cels.2017.08.013

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