Cargando…

Elusive Role of the CD94/NKG2C NK Cell Receptor in the Response to Cytomegalovirus: Novel Experimental Observations in a Reporter Cell System

Human cytomegalovirus (HCMV) infection promotes the differentiation and persistent expansion of a mature NK cell subset, which displays high surface levels of the activating CD94/NKG2C NK cell receptor, together with additional distinctive phenotypic and functional features. The mechanisms underlyin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pupuleku, Aldi, Costa-García, Marcel, Farré, Domènec, Hengel, Hartmut, Angulo, Ana, Muntasell, Aura, López-Botet, Miguel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660692/ https://www.ncbi.nlm.nih.gov/pubmed/29114247 http://dx.doi.org/10.3389/fimmu.2017.01317

Ejemplares similares

Human Cytomegalovirus Antigen Presentation by HLA-DR+ NKG2C+ Adaptive NK Cells Specifically Activates Polyfunctional Effector Memory CD4+ T Lymphocytes
por: Costa-García, Marcel, et al.
Publicado: (2019)

Dual Role of Natural Killer Cells on Graft Rejection and Control of Cytomegalovirus Infection in Renal Transplantation
por: López-Botet, Miguel, et al.
Publicado: (2017)

Priming of NK Cell Anti-Viral Effector Mechanisms by Direct Recognition of Human Cytomegalovirus
por: Muntasell, Aura, et al.
Publicado: (2013)

Complete genomic characterization of a new KLRC2 allele, NKG2C*03
por: Asenjo, Judit, et al.
Publicado: (2021)

Diversity of NKG2C genotypes in a European population: Conserved and recombinant haplotypes in the coding, promoter, and 3′‐untranslated regions
por: Asenjo, Judit, et al.
Publicado: (2022)

Divergent Traits and Ligand-Binding Properties of the Cytomegalovirus CD48 Gene Family
por: Martínez-Vicente, Pablo, et al.
Publicado: (2020)

Subversion of natural killer cell responses by a cytomegalovirus-encoded soluble CD48 decoy receptor
por: Martínez-Vicente, Pablo, et al.
Publicado: (2019)

The CD94/NKG2A inhibitory receptor educates uterine NK cells to optimize pregnancy outcomes in humans and mice
por: Shreeve, Norman, et al.
Publicado: (2021)

NK cells eliminate Epstein-Barr virus bound to B cells through a specific antibody-mediated uptake
por: Alari-Pahissa, Elisenda, et al.
Publicado: (2021)

NK cell activation through the NKG2D ligand MULT-1 is selectively prevented by the glycoprotein encoded by mouse cytomegalovirus gene m145
por: Krmpotic, Astrid, et al.
Publicado: (2005)

Differential Expression of NK Receptors CD94 and NKG2A by T Cells in Rheumatoid Arthritis Patients in Remission Compared to Active Disease
por: Walsh, Ceara E., et al.
Publicado: (2011)

Cytotoxicity of CD56(bright) NK Cells towards Autologous Activated CD4(+) T Cells Is Mediated through NKG2D, LFA-1 and TRAIL and Dampened via CD94/NKG2A
por: Nielsen, Natasja, et al.
Publicado: (2012)

Recognition of the Class Ib Molecule Qa-1(b) by Putative Activating Receptors Cd94/Nkg2c and Cd94/Nkg2e on Mouse Natural Killer Cells
por: Vance, Russell E., et al.
Publicado: (1999)

High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation
por: Huisman, Brooke D., et al.
Publicado: (2023)

Cytomegalovirus m154 Hinders CD48 Cell-Surface Expression and Promotes Viral Escape from Host Natural Killer Cell Control
por: Zarama, Angela, et al.
Publicado: (2014)

Publisher Correction: High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation
por: Huisman, Brooke D., et al.
Publicado: (2023)

The NK cell checkpoint NKG2A maintains expansion capacity of human NK cells
por: Kaulfuss, Meike, et al.
Publicado: (2023)

NKG2C+ NK Cells for Immunotherapy of Glioblastoma Multiforme
por: Murad, Shafiq, et al.
Publicado: (2022)

NKG2A Complexed with CD94 Defines a Novel Inhibitory Natural Killer Cell Receptor
por: Brooks, Andrew G., et al.
Publicado: (1997)

Characterization of KIR (+) NK cell subsets with a monoclonal antibody selectively recognizing KIR2DL1 and blocking the specific interaction with HLA‐C
por: Meazza, Raffaella, et al.
Publicado: (2022)

Shedding Light on the Elusive Role of Endothelial Cells in Cytomegalovirus Dissemination
por: Sacher, Torsten, et al.
Publicado: (2011)

Potential of the NKG2D/NKG2DL Axis in NK Cell-Mediated Clearance of the HIV-1 Reservoir
por: Desimio, Maria G., et al.
Publicado: (2019)

A Single-Cell Approach to the Elusive Latent Human Cytomegalovirus Transcriptome
por: Goodrum, Felicia, et al.
Publicado: (2018)

Circulating CD56+ NKG2D+ NK cells and postoperative fertility in ovarian endometrioma
por: Liu, Zhi-Qin, et al.
Publicado: (2020)

Human Cytomegalovirus and Autoimmune Disease
por: Halenius, Anne, et al.
Publicado: (2014)

Inhibitory NKG2A(+) and absent activating NKG2C(+) NK cell responses are associated with the development of EBV(+) lymphomas
por: Vietzen, Hannes, et al.
Publicado: (2023)

CD94 Is Essential for NK Cell-Mediated Resistance to a Lethal Viral Disease
por: Fang, Min, et al.
Publicado: (2011)

Bispecific NKG2D-CD3 and NKG2D-CD16 fusion proteins for induction of NK and T cell reactivity against acute myeloid leukemia
por: Märklin, Melanie, et al.
Publicado: (2019)

Polyclonal Expansion of NKG2C(+) NK Cells in TAP-Deficient Patients
por: Béziat, Vivien, et al.
Publicado: (2015)

NKG2A is a NK cell exhaustion checkpoint for HCV persistence
por: Zhang, Chao, et al.
Publicado: (2019)

High Metabolic Function and Resilience of NKG2A-Educated NK Cells
por: Highton, Andrew J., et al.
Publicado: (2020)

Responsiveness to Influenza Vaccination Correlates with NKG2C-Expression on NK Cells
por: Riese, Peggy, et al.
Publicado: (2020)

Dissection of the NKG2C NK cell response against Puumala Orthohantavirus
por: Vietzen, Hannes, et al.
Publicado: (2021)

Cytomegalovirus restricts ICOSL expression on antigen-presenting cells disabling T cell co-stimulation and contributing to immune evasion
por: Angulo, Guillem, et al.
Publicado: (2021)

Chronic NKG2D Engagement In Vivo Differentially Impacts NK Cell Responsiveness by Activating NK Receptors
por: Koch, Christine, et al.
Publicado: (2017)

Circulating NKG2A–NKG2D+ CD56dimCD16+ Natural Killer (NK) Cells as Mediators of Functional Immunosurveillance in Kidney Transplant Recipients
por: Zhu, Li, et al.
Publicado: (2020)

Increased serum NKG2D-ligands and downregulation of NKG2D in peripheral blood NK cells of patients with major burns
por: Haik, Josef, et al.
Publicado: (2015)

NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development
por: Jelenčić, Vedrana, et al.
Publicado: (2018)

Haplotype-Based Analysis of KIR-Gene Profiles in a South European Population—Distribution of Standard and Variant Haplotypes, and Identification of Novel Recombinant Structures
por: Cisneros, Elisa, et al.
Publicado: (2020)

Novel Role of 3’UTR-Embedded Alu Elements as Facilitators of Processed Pseudogene Genesis and Host Gene Capture by Viral Genomes
por: Farré, Domènec, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_irs8q92405e3b46b8rftvvcdda