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Clozapine, chlorpromazine and risperidone dose-dependently reduce emotional hyperthermia, a biological marker of salience

RATIONALE: We recently introduced a new rat model of emotional hyperthermia in which a salient stimulus activates brown adipose tissue (BAT) thermogenesis and tail artery constriction. Antipsychotic drugs, both classical and second generation, act to reduce excessive assignment of salience to object...

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Detalles Bibliográficos
Autores principales: Blessing, William W., Blessing, Esther M., Mohammed, Mazher, Ootsuka, Youichirou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660844/
https://www.ncbi.nlm.nih.gov/pubmed/28812124
http://dx.doi.org/10.1007/s00213-017-4710-x