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Ataxia telangiectasia and rad3 related (ATR)-promyelocytic leukemia protein (PML) pathway of the DNA damage response in the brain of rats administered arsenic trioxide

To examine the in vivo responses of promyelocytic leukemia protein (PML) to arsenic, rats (male, 6 weeks old, Sprague Dawley) were administered a single intraperitoneal dose of 5 mg/kg arsenic trioxide (ATO). The protein was examined in the heart, lung, liver, and brain 6 and 48 hours after administ...

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Detalles Bibliográficos
Autores principales:	Watanabe, Ryo, Unuma, Kana, Noritake, Kanako, Funakoshi, Takeshi, Aki, Toshihiko, Uemura, Koichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Japanese Society of Toxicologic Pathology 2017
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660956/ https://www.ncbi.nlm.nih.gov/pubmed/29097844 http://dx.doi.org/10.1293/tox.2017-0020

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