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Wnt and Hedgehog Signaling Regulate the Differentiation of F9 Cells into Extraembryonic Endoderm

Mouse F9 cells differentiate into primitive extraembryonic endoderm (PrE) when treated with retinoic acid (RA), and this is accompanied by an up-regulation of Gata6. The role of the GATA6 network in PrE differentiation is known, and we have shown it directly activates Wnt6. Canonical Wnt/β-catenin s...

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Detalles Bibliográficos
Autores principales:	Deol, Gurjoth S. J., Cuthbert, Tina N., Gatie, Mohamed I., Spice, Danielle M., Hilton, Lindsay R., Kelly, Gregory M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660979/ https://www.ncbi.nlm.nih.gov/pubmed/29119099 http://dx.doi.org/10.3389/fcell.2017.00093

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