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B Cells Are Indispensable for a Novel Mouse Model of Primary Sjögren’s Syndrome

Primary Sjögren’s syndrome (pSS) is characterized by a panel of autoantibodies, while it is not clear whether B cells and autoantibodies play an essential role in pathogenesis of the disease. Here, we report a novel mouse model for pSS which is induced by immunization with the Ro60_316-335 peptide c...

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Detalles Bibliográficos
Autores principales: Zheng, Junfeng, Huang, Qiaoniang, Huang, Renliang, Deng, Fengyuan, Yue, Xiaoyang, Yin, Junping, Zhao, Wenjie, Chen, Yan, Wen, Lifang, Zhou, Jun, Huang, Renda, Riemekasten, Gabriela, Liu, Zuguo, Petersen, Frank, Yu, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661054/
https://www.ncbi.nlm.nih.gov/pubmed/29118759
http://dx.doi.org/10.3389/fimmu.2017.01384

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