Inhibition of HIF1α and PDK Induces Cell Death of Glioblastoma Multiforme

Glioblastoma multiforme (GBM) is the most common and aggressive form of brain tumors. GBMs, like other tumors, rely relatively less on mitochondrial oxidative phosphorylation (OXPHOS) and utilize more aerobic glycolysis, and this metabolic shift becomes augmented under hypoxia. In the present study,...

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Detalles Bibliográficos
Autores principales: Han, Jiwon Esther, Lim, Pyung Won, Na, Chul Min, Choi, You Sik, Lee, Joo Young, Kim, Yona, Park, Hyung Woo, Moon, Hyo Eun, Heo, Man Seung, Park, Hye Ran, Kim, Dong Gyu, Paek, Sun Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661062/
https://www.ncbi.nlm.nih.gov/pubmed/29093638
http://dx.doi.org/10.5607/en.2017.26.5.295

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