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Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia

Granular cell tumor (GCT) is a neoplasm of Schwann cell origin. Its presence in the aerodigestive tract is uncommon and becomes a diagnostic challenge on initial presentation. Our case is of a 59-year-old woman who presented to the emergency department with a history of productive cough and dyspnea...

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Autores principales: Farooqui, Samid M., Khan, Muhammad S., Adhikari, Laura, Doshi, Viral
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661083/
https://www.ncbi.nlm.nih.gov/pubmed/29163998
http://dx.doi.org/10.1155/2017/8513702
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author Farooqui, Samid M.
Khan, Muhammad S.
Adhikari, Laura
Doshi, Viral
author_facet Farooqui, Samid M.
Khan, Muhammad S.
Adhikari, Laura
Doshi, Viral
author_sort Farooqui, Samid M.
collection PubMed
description Granular cell tumor (GCT) is a neoplasm of Schwann cell origin. Its presence in the aerodigestive tract is uncommon and becomes a diagnostic challenge on initial presentation. Our case is of a 59-year-old woman who presented to the emergency department with a history of productive cough and dyspnea associated with fever and chest pain. An initial chest X-ray (CXR) showed a right middle lobe consolidation with follow-up Computed Tomography (CT) scan showing a mass in the right bronchus. Bronchoscopy revealed a polypoid, sessile granular mass in the right bronchus intermedius with multiple white lesions in trachea, left main bronchus, and right upper bronchi. Histology revealed a benign GCT. Bronchoalveolar lavage from the right middle lobe grew Streptococcus pneumoniae. Patient was treated with intravenous levofloxacin during hospital stay and discharged on a 7-day course of oral antibiotics to be followed as outpatient but was lost to follow-up. GCT can present as a polypoid tumor causing recurrent postobstructive pneumonia. Surgical resection is the most successful treatment option. The tumor is more common in third and fourth decade of life and our patient is the oldest patient, according to our knowledge, to have a GCT.
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spelling pubmed-56610832017-11-21 Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia Farooqui, Samid M. Khan, Muhammad S. Adhikari, Laura Doshi, Viral Case Rep Pulmonol Case Report Granular cell tumor (GCT) is a neoplasm of Schwann cell origin. Its presence in the aerodigestive tract is uncommon and becomes a diagnostic challenge on initial presentation. Our case is of a 59-year-old woman who presented to the emergency department with a history of productive cough and dyspnea associated with fever and chest pain. An initial chest X-ray (CXR) showed a right middle lobe consolidation with follow-up Computed Tomography (CT) scan showing a mass in the right bronchus. Bronchoscopy revealed a polypoid, sessile granular mass in the right bronchus intermedius with multiple white lesions in trachea, left main bronchus, and right upper bronchi. Histology revealed a benign GCT. Bronchoalveolar lavage from the right middle lobe grew Streptococcus pneumoniae. Patient was treated with intravenous levofloxacin during hospital stay and discharged on a 7-day course of oral antibiotics to be followed as outpatient but was lost to follow-up. GCT can present as a polypoid tumor causing recurrent postobstructive pneumonia. Surgical resection is the most successful treatment option. The tumor is more common in third and fourth decade of life and our patient is the oldest patient, according to our knowledge, to have a GCT. Hindawi 2017 2017-10-15 /pmc/articles/PMC5661083/ /pubmed/29163998 http://dx.doi.org/10.1155/2017/8513702 Text en Copyright © 2017 Samid M. Farooqui et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Farooqui, Samid M.
Khan, Muhammad S.
Adhikari, Laura
Doshi, Viral
Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia
title Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia
title_full Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia
title_fullStr Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia
title_full_unstemmed Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia
title_short Multifocal Pulmonary Granular Cell Tumor Presenting with Postobstructive Pneumonia
title_sort multifocal pulmonary granular cell tumor presenting with postobstructive pneumonia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661083/
https://www.ncbi.nlm.nih.gov/pubmed/29163998
http://dx.doi.org/10.1155/2017/8513702
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