Cargando…

Mechanisms of P-Glycoprotein Modulation by Semen Strychni Combined with Radix Paeoniae Alba

Semen Strychni has been extensively used as a Chinese herb, but its therapeutic window is narrowed by the strong toxicity of the compound, which limits its effectiveness. Radix Paeoniae Alba has been reported to reduce the toxic effects and increase the therapeutic effects of Semen Strychni, but the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Li-Li, Guan, Yong-Mei, Lu, Xue-Ping, Liang, Xin-Li, Chen, Li-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661092/ https://www.ncbi.nlm.nih.gov/pubmed/29234368 http://dx.doi.org/10.1155/2017/1743870

Ejemplares similares

Prophylactic Neuroprotection of Total Glucosides of Paeoniae Radix Alba against Semen Strychni-Induced Neurotoxicity in Rats: Suppressing Oxidative Stress and Reducing the Absorption of Toxic Components
por: Li, Shujuan, et al.
Publicado: (2018)

Efficacy, Chemical Constituents, and Pharmacological Actions of Radix Paeoniae Rubra and Radix Paeoniae Alba
por: Tan, Yu-Qing, et al.
Publicado: (2020)

Exploring the Target and Mechanism of Radix Paeoniae Alba on Sjogren’s Syndrome
por: Wu, Fangping, et al.
Publicado: (2023)

Paeoniae alba Radix Promotes Peripheral Nerve Regeneration
por: Huang, Kun-Shan, et al.
Publicado: (2011)

Receptor and transporter binding and activity profiles of albiflorin extracted from Radix paeoniae Alba
por: Jin, Zeng-liang, et al.
Publicado: (2016)

Carbon Dots from Paeoniae Radix Alba Carbonisata: Hepatoprotective Effect
por: Zhao, Yusheng, et al.
Publicado: (2020)

Investigation of Efficacy Enhancing and Toxicity Reducing Mechanism of Combination of Aconiti Lateralis Radix Praeparata and Paeoniae Radix Alba in Adjuvant-Induced Arthritis Rats by Metabolomics
por: Xie, Yun-fei, et al.
Publicado: (2019)

Quick comparison of Radix Paeonia Alba, Radix Paeonia Rubra, and Cortex Moutan by high performance liquid chromatography coupled with monolithic columns and their chemical pattern recognition
por: Chunnian, He, et al.
Publicado: (2012)

Radix Paeoniae Alba attenuates Radix Bupleuri-induced hepatotoxicity by modulating gut microbiota to alleviate the inhibition of saikosaponins on glutathione synthetase
por: Chen, Congcong, et al.
Publicado: (2023)

Radix paeoniae alba polysaccharide attenuates lipopolysaccharide-induced intestinal injury by regulating gut microbiota
por: Li, Aoyun, et al.
Publicado: (2023)

Single Standard Substance for the Simultaneous Determination of Eleven Components in the Extract of Paeoniae Radix Alba (Root of Paeonia lactiflora Pall.)
por: Shen, Menglan, et al.
Publicado: (2021)

Dissipation Behavior of Three Fungicides during the Industrial Processing of Paeoniae Radix Alba and Associated Processing Factors
por: Li, Sheng-Nan, et al.
Publicado: (2019)

Inhibitory effect of an aqueous extract of Radix Paeoniae Alba on calcium oxalate nephrolithiasis in a rat model
por: Li, Xiaoran, et al.
Publicado: (2017)

Systematic pharmacology-based strategy to explore the mechanism of Semen Strychni for treatment of papillary thyroid carcinoma
por: Mao, Jingxin, et al.
Publicado: (2023)

Network Pharmacology Analysis of the Identification of Phytochemicals and Therapeutic Mechanisms of Paeoniae Radix Alba for the Treatment of Asthma
por: Wang, Jingwei, et al.
Publicado: (2021)

The Potential Hepatoprotective Effect of Paeoniae Radix Alba in Thioacetamide-Induced Acute Liver Injury in Rats
por: Shin, Mi-Rae, et al.
Publicado: (2022)

One of the active ingredients in Paeoniae Radix Alba functions as JAK1 inhibitor in rheumatoid arthritis
por: Xiao, Lu, et al.
Publicado: (2022)

Evaluation of the Influence of Sulfur-Fumigated Paeoniae Radix Alba on the Quality of Si Wu Tang by Chromatographic and Chemometric Analysis
por: Pei, Ke, et al.
Publicado: (2016)

High-Throughput Metabolomics Integrated Network Pharmacology Reveals the Underlying Mechanism of Paeoniae Radix Alba Treating Rheumatoid Arthritis
por: Liu, Lei, et al.
Publicado: (2022)

Isoliquiritigenin Alleviates Semen Strychni-Induced Neurotoxicity by Restoring the Metabolic Pathway of Neurotransmitters in Rats
por: Wang, Lu, et al.
Publicado: (2021)

Pharmacokinetics-Based Chronoefficacy of Semen Strychni and Tripterygium Glycoside Tablet Against Rheumatoid Arthritis
por: Lin, Jingpan, et al.
Publicado: (2021)

Exploring the mechanism of Semen Strychni in treating amyotrophic lateral sclerosis based on network pharmacology
por: Tang, Xiaohui, et al.
Publicado: (2023)

Anti-Inflammatory Effects, SAR, and Action Mechanism of Monoterpenoids from Radix Paeoniae Alba on LPS-Stimulated RAW 264.7 Cells
por: Bi, Xiaoxu, et al.
Publicado: (2017)

The Potential Effects of Dielectric Barrier Discharge Plasma on the Extraction Efficiency of Bioactive Compounds in Radix Paeoniae Alba
por: Jin, Tao, et al.
Publicado: (2021)

Detection of Sulfur-Fumigated Paeoniae Alba Radix in Complex Preparations by High Performance Liquid Chromatography Tandem Mass Spectrometry
por: Wu, Jie, et al.
Publicado: (2012)

Studies on the Changes of Pharmacokinetics Behaviors of Phytochemicals and the Influence on Endogenous Metabolites After the Combination of Radix Bupleuri and Radix Paeoniae Alba Based on Multi-Component Pharmacokinetics and Metabolomics
por: Chen, Congcong, et al.
Publicado: (2021)

Antipyretic activity of Radix paeoniae
por: Motwani, Sapna, et al.
Publicado: (2007)

Identification of metabolites of Radix Paeoniae Alba extract in rat bile, plasma and urine by ultra-performance liquid chromatography–quadrupole time-of-flight mass spectrometry
por: Chen, Zheng-Wei, et al.
Publicado: (2014)

Uncovering the mechanism of Radix Paeoniae Alba in the treatment of restless legs syndrome based on network pharmacology and molecular docking
por: Liu, Jun, et al.
Publicado: (2022)

Transcriptomics- and metabolomics-based integration analyses revealed the potential pharmacological effects and functional pattern of in vivo Radix Paeoniae Alba administration
por: Wang, Sining, et al.
Publicado: (2020)

Antihypertensive Effect of Radix Paeoniae Alba in Spontaneously Hypertensive Rats and Excessive Alcohol Intake and High Fat Diet Induced Hypertensive Rats
por: Su-Hong, Chen, et al.
Publicado: (2015)

UPLC-PDA determination of paeoniflorin in rat plasma following the oral administration of Radix Paeoniae Alba and its effects on rats with collagen-induced arthritis
por: WU, DAN, et al.
Publicado: (2014)

Network pharmacology and molecular docking technology for exploring the effect and mechanism of Radix Bupleuri and Radix Paeoniae Alba herb-pair on anti-hepatitis: A review
por: Huang, Long, et al.
Publicado: (2023)

Radix Paeoniae Rubra and Radix Paeoniae Alba Attenuate CCl(4)-Induced Acute Liver Injury: An Ultra-Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS) Based Metabolomic Approach for the Pharmacodynamic Study of Traditional Chinese Medicines (TCMs)
por: Wang, Rui, et al.
Publicado: (2012)

Uncovering the mechanism of the effects of Paeoniae Radix Alba on iron-deficiency anaemia through a network pharmacology-based strategy
por: Ye, Xian-wen, et al.
Publicado: (2020)

Hydroxyethyl Cellulose-Based Hydrogels as Controlled Release Carriers for Amorphous Solid Dispersion of Bioactive Components of Radix Paeonia Alba
por: Naeem, Abid, et al.
Publicado: (2023)

Renoprotective Effects of Total Glucosides from Paeony against Nephrotoxicity Induced by Total Alkaloids from Semen Strychni
por: Lv, Mingming, et al.
Publicado: (2017)

The Correlation between Chemical Composition, as Determined by UPLC-TOF-MS, and Acute Toxicity of Veratrum nigrum L. and Radix paeoniae alba
por: Zhang, Xianxie, et al.
Publicado: (2014)

The Inhibition of Mast Cell Activation of Radix Paeoniae alba Extraction Identified by TCRP Based and Conventional Cell Function Assay Systems
por: Fu, Huiying, et al.
Publicado: (2016)

Antithrombotic Effect and Mechanism of Radix Paeoniae Rubra
por: Xie, Pingyao, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_gmfjuulh8s69bideocmd9dr4pd