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Loss of SH3GL2 promotes the migration and invasion behaviours of glioblastoma cells through activating the STAT3/MMP2 signalling

SH3GL2 (Src homology 3 (SH3) domain GRB2‐like 2) is mainly expressed in the central nervous system and regarded as a tumour suppressor in human glioma. However, the molecular mechanism of the SH3GL2 protein involved in malignant behaviours of human glioma has not been elucidated. In this study, we t...

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Detalles Bibliográficos
Autores principales: Zhu, Yufu, Zhang, Xiang, Wang, Lei, Ji, Zhe, Xie, Manyi, Zhou, Xinyu, Liu, Zhiyi, Shi, Hengliang, Yu, Rutong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661104/
https://www.ncbi.nlm.nih.gov/pubmed/28470949
http://dx.doi.org/10.1111/jcmm.13184