HIF‐2α regulates non‐canonical glutamine metabolism via activation of PI3K/mTORC2 pathway in human pancreatic ductal adenocarcinoma

Hypoxia‐inducible factor‐2α (HIF‐2α) plays an important role in increasing cancer progression and distant metastasis in a variety of tumour types. We aimed to investigate its biological function and clinical significance in human pancreatic ductal adenocarcinoma (PDAC). A total of 283 paired PDAC ti...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Wenzhu, Chen, Changhao, Zhao, Xiaohui, Ye, Huilin, Zhao, Yue, Fu, Zhiqiang, Pan, Wenwei, Zheng, Shangyou, Wei, Lusheng, Nong, Tianwen, Li, Zhihua, Chen, Rufu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661146/
https://www.ncbi.nlm.nih.gov/pubmed/28544376
http://dx.doi.org/10.1111/jcmm.13202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661146/
https://www.ncbi.nlm.nih.gov/pubmed/28544376
http://dx.doi.org/10.1111/jcmm.13202

Ejemplares similares