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PTEN inhibits replicative senescence‐induced MMP‐1 expression by regulating NOX4‐mediated ROS in human dermal fibroblasts

The biological function of NADPH oxidase (NOX) is the generation of reactive oxygen species (ROS). ROS, primarily arising from oxidative cell metabolism, play a major role in both chronological ageing and photoageing. ROS in extrinsic and intrinsic skin ageing may be assumed to induce the expression...

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Detalles Bibliográficos
Autores principales: Noh, Eun‐Mi, Kim, Jeong‐Mi, Hong, On‐Yu, Song, Hyun‐Kyung, Kim, Jong‐Suk, Kwon, Kang‐Beom, Lee, Young‐Rae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661253/
https://www.ncbi.nlm.nih.gov/pubmed/28557373
http://dx.doi.org/10.1111/jcmm.13220