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An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit
CONTEXT: Myocardial injury during cardiac surgery on cardiopulmonary bypass (CPB) is a major determinant of morbidity and mortality. Preclinical and clinical evidence of dose- and time-related cardioprotective effects of volatile anesthetic drugs exist and their use during the whole surgery duration...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661307/ https://www.ncbi.nlm.nih.gov/pubmed/28994673 http://dx.doi.org/10.4103/aca.ACA_50_17 |
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author | De Simone, Francesco Cassarà, Luigi Sardo, Salvatore Scarparo, Elena Saleh, Omar Nigro Neto, Caetano Zangrillo, Alberto Landoni, Giovanni |
author_facet | De Simone, Francesco Cassarà, Luigi Sardo, Salvatore Scarparo, Elena Saleh, Omar Nigro Neto, Caetano Zangrillo, Alberto Landoni, Giovanni |
author_sort | De Simone, Francesco |
collection | PubMed |
description | CONTEXT: Myocardial injury during cardiac surgery on cardiopulmonary bypass (CPB) is a major determinant of morbidity and mortality. Preclinical and clinical evidence of dose- and time-related cardioprotective effects of volatile anesthetic drugs exist and their use during the whole surgery duration could improve perioperative cardiac protection. Even if administering volatile agents during CPB are relatively easy, technical problems, such as waste gas scavenging, may prevent safe and manageable administration of halogenated vapors during CPB. AIMS: The aim of this study is to improve the safe administration of volatile anesthesia during CPB. SETTINGS AND DESIGN: Tertiary teaching hospital. SUBJECTS AND METHODS: We describe an original device that collects and disposes of any volatile anesthetic vapors present in the exit stream of the oxygenator, hence preventing its dispersal into the operating theatre environment and adaptively regulates pressure of oxygenator chamber in the CPB circuit. RESULTS: We have so far applied a prototype of this device in more than 1300 adult cardiac surgery patients who received volatile anesthetics during the CPB phase. CONCLUSIONS: Widespread implementation of scavenging system like the one we designed may facilitate the perfusionist and the anesthesiologist in delivering these cardioprotective drugs with beneficial impact on patients’ outcome without compromising on safety. |
format | Online Article Text |
id | pubmed-5661307 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-56613072017-11-09 An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit De Simone, Francesco Cassarà, Luigi Sardo, Salvatore Scarparo, Elena Saleh, Omar Nigro Neto, Caetano Zangrillo, Alberto Landoni, Giovanni Ann Card Anaesth Original Article CONTEXT: Myocardial injury during cardiac surgery on cardiopulmonary bypass (CPB) is a major determinant of morbidity and mortality. Preclinical and clinical evidence of dose- and time-related cardioprotective effects of volatile anesthetic drugs exist and their use during the whole surgery duration could improve perioperative cardiac protection. Even if administering volatile agents during CPB are relatively easy, technical problems, such as waste gas scavenging, may prevent safe and manageable administration of halogenated vapors during CPB. AIMS: The aim of this study is to improve the safe administration of volatile anesthesia during CPB. SETTINGS AND DESIGN: Tertiary teaching hospital. SUBJECTS AND METHODS: We describe an original device that collects and disposes of any volatile anesthetic vapors present in the exit stream of the oxygenator, hence preventing its dispersal into the operating theatre environment and adaptively regulates pressure of oxygenator chamber in the CPB circuit. RESULTS: We have so far applied a prototype of this device in more than 1300 adult cardiac surgery patients who received volatile anesthetics during the CPB phase. CONCLUSIONS: Widespread implementation of scavenging system like the one we designed may facilitate the perfusionist and the anesthesiologist in delivering these cardioprotective drugs with beneficial impact on patients’ outcome without compromising on safety. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5661307/ /pubmed/28994673 http://dx.doi.org/10.4103/aca.ACA_50_17 Text en Copyright: © 2017 Annals of Cardiac Anaesthesia http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article De Simone, Francesco Cassarà, Luigi Sardo, Salvatore Scarparo, Elena Saleh, Omar Nigro Neto, Caetano Zangrillo, Alberto Landoni, Giovanni An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit |
title | An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit |
title_full | An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit |
title_fullStr | An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit |
title_full_unstemmed | An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit |
title_short | An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit |
title_sort | innovative technique to improve safety of volatile anesthetics suction from the cardiopulmonary bypass circuit |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661307/ https://www.ncbi.nlm.nih.gov/pubmed/28994673 http://dx.doi.org/10.4103/aca.ACA_50_17 |
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