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An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit

CONTEXT: Myocardial injury during cardiac surgery on cardiopulmonary bypass (CPB) is a major determinant of morbidity and mortality. Preclinical and clinical evidence of dose- and time-related cardioprotective effects of volatile anesthetic drugs exist and their use during the whole surgery duration...

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Autores principales: De Simone, Francesco, Cassarà, Luigi, Sardo, Salvatore, Scarparo, Elena, Saleh, Omar, Nigro Neto, Caetano, Zangrillo, Alberto, Landoni, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661307/
https://www.ncbi.nlm.nih.gov/pubmed/28994673
http://dx.doi.org/10.4103/aca.ACA_50_17
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author De Simone, Francesco
Cassarà, Luigi
Sardo, Salvatore
Scarparo, Elena
Saleh, Omar
Nigro Neto, Caetano
Zangrillo, Alberto
Landoni, Giovanni
author_facet De Simone, Francesco
Cassarà, Luigi
Sardo, Salvatore
Scarparo, Elena
Saleh, Omar
Nigro Neto, Caetano
Zangrillo, Alberto
Landoni, Giovanni
author_sort De Simone, Francesco
collection PubMed
description CONTEXT: Myocardial injury during cardiac surgery on cardiopulmonary bypass (CPB) is a major determinant of morbidity and mortality. Preclinical and clinical evidence of dose- and time-related cardioprotective effects of volatile anesthetic drugs exist and their use during the whole surgery duration could improve perioperative cardiac protection. Even if administering volatile agents during CPB are relatively easy, technical problems, such as waste gas scavenging, may prevent safe and manageable administration of halogenated vapors during CPB. AIMS: The aim of this study is to improve the safe administration of volatile anesthesia during CPB. SETTINGS AND DESIGN: Tertiary teaching hospital. SUBJECTS AND METHODS: We describe an original device that collects and disposes of any volatile anesthetic vapors present in the exit stream of the oxygenator, hence preventing its dispersal into the operating theatre environment and adaptively regulates pressure of oxygenator chamber in the CPB circuit. RESULTS: We have so far applied a prototype of this device in more than 1300 adult cardiac surgery patients who received volatile anesthetics during the CPB phase. CONCLUSIONS: Widespread implementation of scavenging system like the one we designed may facilitate the perfusionist and the anesthesiologist in delivering these cardioprotective drugs with beneficial impact on patients’ outcome without compromising on safety.
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spelling pubmed-56613072017-11-09 An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit De Simone, Francesco Cassarà, Luigi Sardo, Salvatore Scarparo, Elena Saleh, Omar Nigro Neto, Caetano Zangrillo, Alberto Landoni, Giovanni Ann Card Anaesth Original Article CONTEXT: Myocardial injury during cardiac surgery on cardiopulmonary bypass (CPB) is a major determinant of morbidity and mortality. Preclinical and clinical evidence of dose- and time-related cardioprotective effects of volatile anesthetic drugs exist and their use during the whole surgery duration could improve perioperative cardiac protection. Even if administering volatile agents during CPB are relatively easy, technical problems, such as waste gas scavenging, may prevent safe and manageable administration of halogenated vapors during CPB. AIMS: The aim of this study is to improve the safe administration of volatile anesthesia during CPB. SETTINGS AND DESIGN: Tertiary teaching hospital. SUBJECTS AND METHODS: We describe an original device that collects and disposes of any volatile anesthetic vapors present in the exit stream of the oxygenator, hence preventing its dispersal into the operating theatre environment and adaptively regulates pressure of oxygenator chamber in the CPB circuit. RESULTS: We have so far applied a prototype of this device in more than 1300 adult cardiac surgery patients who received volatile anesthetics during the CPB phase. CONCLUSIONS: Widespread implementation of scavenging system like the one we designed may facilitate the perfusionist and the anesthesiologist in delivering these cardioprotective drugs with beneficial impact on patients’ outcome without compromising on safety. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5661307/ /pubmed/28994673 http://dx.doi.org/10.4103/aca.ACA_50_17 Text en Copyright: © 2017 Annals of Cardiac Anaesthesia http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
De Simone, Francesco
Cassarà, Luigi
Sardo, Salvatore
Scarparo, Elena
Saleh, Omar
Nigro Neto, Caetano
Zangrillo, Alberto
Landoni, Giovanni
An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit
title An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit
title_full An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit
title_fullStr An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit
title_full_unstemmed An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit
title_short An Innovative Technique to Improve Safety of Volatile Anesthetics Suction from the Cardiopulmonary Bypass Circuit
title_sort innovative technique to improve safety of volatile anesthetics suction from the cardiopulmonary bypass circuit
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661307/
https://www.ncbi.nlm.nih.gov/pubmed/28994673
http://dx.doi.org/10.4103/aca.ACA_50_17
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