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Distribution of uridine diphosphate glucuronosyltransferase 1A polymorphisms and their role in irinotecan-induced toxicity in patients with cancer

Uridine diphosphate glucuronosyltransferase 1A (UGT1A1), which affects irinotecan metabolism, has been associated with severe adverse reactions in patients with cancer treated with irinotecan. However, neither large-scale analysis of the distribution of UGT1A1 polymorphisms, nor standardized assessm...

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Detalles Bibliográficos
Autores principales:	Wang, Yang, Yi, Cuihua, Wang, Yawei, Li, Hui, Li, Bei, Wang, Dan, Du, Jintong, Liu, Lian, Wang, Xiuwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661374/ https://www.ncbi.nlm.nih.gov/pubmed/29113203 http://dx.doi.org/10.3892/ol.2017.6933

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