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Intron-specific shRNA-mediated downregulation of survivin and promotion of apoptosis in HeLa cells

Overexpression of the survivin gene contributes to tumorigenesis; it has been recognized as an important target for cancer therapy. In the present study, survivin expression was suppressed using recombinant plasmid mediated short hairpin RNAs (shRNAs) that were constructed to target exonic or intron...

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Detalles Bibliográficos
Autores principales:	Wang, Yue-Li, Shao, Xin, Wang, Fa, Zeng, Liang, Hu, Liang, Cui, Shi-Quan, Hou, Gan, Huang, Di-Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661408/ https://www.ncbi.nlm.nih.gov/pubmed/29113228 http://dx.doi.org/10.3892/ol.2017.6996

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