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Central role of lactate and proton in cancer cell resistance to glucose deprivation and its clinical translation
Targeting common weaknesses of cancer is an important strategy for cancer therapy. Glucose is a nutrient that maintains essential cellular metabolism, supporting cancer cell survival, growth and proliferation. Depriving glucose rapidly kills cancer cells. Most cancer cells possess a feature called W...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661620/ https://www.ncbi.nlm.nih.gov/pubmed/29263910 http://dx.doi.org/10.1038/sigtrans.2016.47 |