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Deubiquitylating Nanog: novel role of USP21 in embryonic stem cell maintenance
Recently, three groups independently identified ubiquitin-specific peptidase 21 (USP21) as an efficient deubiquitylase that reverses Nanog polyubiquitylation and stabilizes Nanog protein. In this preview, I have summarized the work of these three groups.
Autor principal: | Pei, Duanqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661622/ https://www.ncbi.nlm.nih.gov/pubmed/29263917 http://dx.doi.org/10.1038/sigtrans.2017.14 |
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