From a retrovirus infection of mice to a long noncoding RNA that induces proto-oncogene transcription and oncogenesis via an epigenetic transcription switch

Here I review the properties of the mouse retroelement VL30-1, which apparently derived from retrotranspostions of a founder VL30 retrovirus that infected the mouse germline after the mouse–human speciation. The VL30-1 gene is transcribed as a long noncoding RNA (lncRNA) with an essential host funct...

Descripción completa

Detalles Bibliográficos
Autor principal: Garen, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661657/
https://www.ncbi.nlm.nih.gov/pubmed/29263895
http://dx.doi.org/10.1038/sigtrans.2016.7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661657/
https://www.ncbi.nlm.nih.gov/pubmed/29263895
http://dx.doi.org/10.1038/sigtrans.2016.7

Ejemplares similares