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Inhibiting cancer cell hallmark features through nuclear export inhibition

Treating cancer through inhibition of nuclear export is one of the best examples of basic research translation into clinical application. Nuclear export factor chromosomal region maintenance 1 (CRM1; Xpo1 and exportin-1) controls cellular localization and function of numerous proteins that are criti...

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Detalles Bibliográficos
Autores principales:	Sun, Qingxiang, Chen, Xueqin, Zhou, Qiao, Burstein, Ezra, Yang, Shengyong, Jia, Da
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661660/ https://www.ncbi.nlm.nih.gov/pubmed/29263896 http://dx.doi.org/10.1038/sigtrans.2016.10

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