Eupatolide inhibits the TGF-β1-induced migration of breast cancer cells via downregulation of SMAD3 phosphorylation and transcriptional repression of ALK5

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The epithelial-mesenchymal transition (EMT) is a hallmark of cancer metastasis, and the associated molecular signaling pathways are regarded as therapeutic targets for cancer treatment. Thus, suppressing EMT with a natural chemical compound may be of therapeutic benefit. Eupatolide is a natural chem...

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Detalles Bibliográficos
Autores principales: Boldbaatar, Ariundavaa, Lee, Sunyi, Han, Sora, Jeong, Ae Lee, Ka, Hye In, Buyanravjikh, Sumiyasuren, Lee, Jeong Hyung, Lim, Jong-Seok, Lee, Myung Sok, Yang, Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661662/
https://www.ncbi.nlm.nih.gov/pubmed/29113242
http://dx.doi.org/10.3892/ol.2017.6957
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