Sensory TRP channels contribute differentially to skin inflammation and persistent itch

Although both persistent itch and inflammation are commonly associated with allergic contact dermatitis (ACD), it is not known if they are mediated by shared or distinct signaling pathways. Here we show that both TRPA1 and TRPV1 channels are required for generating spontaneous scratching in a mouse...

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Detalles Bibliográficos
Autores principales: Feng, Jing, Yang, Pu, Mack, Madison R., Dryn, Dariia, Luo, Jialie, Gong, Xuan, Liu, Shenbin, Oetjen, Landon K., Zholos, Alexander V., Mei, Zhinan, Yin, Shijin, Kim, Brian S., Hu, Hongzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661746/
https://www.ncbi.nlm.nih.gov/pubmed/29081531
http://dx.doi.org/10.1038/s41467-017-01056-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661746/
https://www.ncbi.nlm.nih.gov/pubmed/29081531
http://dx.doi.org/10.1038/s41467-017-01056-8

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