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Frequency and clinical relevance of EGFR mutations and EML4–ALK translocations in octogenarians with non-small cell lung cancer

BACKGROUND: Tyrosine kinase inhibitors (TKIs) have improved response rates in some patients with non-small cell lung cancer (NSCLC), and testing for EGFR mutation and ALK translocation is recommended for all patients with advanced lung adenocarcinoma. The frequency of driver mutations in elderly and...

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Detalles Bibliográficos
Autores principales:	Tufman, Amanda, Kahnert, Kathrin, Duell, Thomas, Kauffmann-Guerrero, Diego, Milger, Katrin, Schneider, Christian, Stump, Julia, Syunyaeva, Zulfiya, Huber, Rudolf Maria, Reu, Simone
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661834/ https://www.ncbi.nlm.nih.gov/pubmed/29123416 http://dx.doi.org/10.2147/OTT.S140472

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