In vivo study of doxorubicin-loaded cell-penetrating peptide-modified pH-sensitive liposomes: biocompatibility, bio-distribution, and pharmacodynamics in BALB/c nude mice bearing human breast tumors

In vivo evaluation of drug delivery vectors is essential for clinical translation. In BALB/c nude mice bearing human breast cancer tumors, we investigated the biocompatibility, pharmacokinetics, and pharmacodynamics of doxorubicin (DOX)-loaded novel cell-penetrating peptide (CPP)-modified pH-sensiti...

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Detalles Bibliográficos
Autores principales: Ding, Yuan, Cui, Wei, Sun, Dan, Wang, Gui-Ling, Hei, Yu, Meng, Shuai, Chen, Jian-Hua, Xie, Ying, Wang, Zhi-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661853/
https://www.ncbi.nlm.nih.gov/pubmed/29123382
http://dx.doi.org/10.2147/DDDT.S149814

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