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Sequence-based prediction of permissive stretches for internal protein tagging and knockdown

BACKGROUND: Internal tagging of proteins by inserting small functional peptides into surface accessible permissive sites has proven to be an indispensable tool for basic and applied science. Permissive sites are typically identified by transposon mutagenesis on a case-by-case basis, limiting scalabi...

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Detalles Bibliográficos
Autores principales: Oesterle, Sabine, Roberts, Tania Michelle, Widmer, Lukas Andreas, Mustafa, Harun, Panke, Sven, Billerbeck, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661948/
https://www.ncbi.nlm.nih.gov/pubmed/29084520
http://dx.doi.org/10.1186/s12915-017-0440-0