Enhanced sleep reverses memory deficits and underlying pathology in drosophila models of Alzheimer's disease

To test the hypothesis that sleep can reverse cognitive impairment during Alzheimer's disease, we enhanced sleep in flies either co-expressing human amyloid precursor protein and Beta-secretase (APP:BACE), or in flies expressing human tau. The ubiquitous expression of APP:BACE or human tau disr...

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Detalles Bibliográficos
Autores principales: Dissel, Stephane, Klose, Markus, Donlea, Jeff, Cao, Lijuan, English, Denis, Winsky-Sommerer, Raphaelle, van Swinderen, Bruno, Shaw, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662006/
https://www.ncbi.nlm.nih.gov/pubmed/29094110
http://dx.doi.org/10.1016/j.nbscr.2016.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662006/
https://www.ncbi.nlm.nih.gov/pubmed/29094110
http://dx.doi.org/10.1016/j.nbscr.2016.09.001

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