TrpA1 activation in peripheral sensory neurons underlies the ionic basis of pain hypersensitivity in response to vinca alkaloids

Chemotherapy induced peripheral neuropathy (CIPN), a side effect of many anti-cancer drugs including the vinca alkaloids, is characterized by a severe pain syndrome that compromises treatment in many patients. Currently there are no effective treatments for this pain syndrome except for the reductio...

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Detalles Bibliográficos
Autores principales: Boiko, Nina, Medrano, Geraldo, Montano, Elizabeth, Jiang, Nan, Williams, Claire R., Madungwe, Ngonidzashe B., Bopassa, Jean C., Kim, Charles C., Parrish, Jay Z., Hargreaves, Kenneth M., Stockand, James D., Eaton, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662086/
https://www.ncbi.nlm.nih.gov/pubmed/29084244
http://dx.doi.org/10.1371/journal.pone.0186888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662086/
https://www.ncbi.nlm.nih.gov/pubmed/29084244
http://dx.doi.org/10.1371/journal.pone.0186888

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