Cargando…

Early structural changes of the heart after experimental polytrauma and hemorrhagic shock

Evidence is emerging that systemic inflammation after trauma drives structural and functional impairment of cardiomyocytes and leads to cardiac dysfunction, thus worsening the outcome of polytrauma patients. This study investigates the structural and molecular changes in heart tissue 4 h after multi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Braun, Christian K., Kalbitz, Miriam, Halbgebauer, Rebecca, Eisele, Philipp, Messerer, David A. C., Weckbach, Sebastian, Schultze, Anke, Braumüller, Sonja, Gebhard, Florian, Huber-Lang, Markus S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662170/ https://www.ncbi.nlm.nih.gov/pubmed/29084268 http://dx.doi.org/10.1371/journal.pone.0187327

Ejemplares similares

Early Detection of Junctional Adhesion Molecule-1 (JAM-1) in the Circulation after Experimental and Clinical Polytrauma
por: Denk, Stephanie, et al.
Publicado: (2015)

A New Experimental Polytrauma Model in Rats: Molecular Characterization of the Early Inflammatory Response
por: Weckbach, Sebastian, et al.
Publicado: (2012)

Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock
por: Chakraborty, Shinjini, et al.
Publicado: (2021)

Complement Factor C5a Inhibits Apoptosis of Neutrophils—A Mechanism in Polytrauma?
por: Ehrnthaller, Christian, et al.
Publicado: (2021)

Thirty-Eight-Negative Kinase 1 Is a Mediator of Acute Kidney Injury in Experimental and Clinical Traumatic Hemorrhagic Shock
por: Halbgebauer, Rebecca, et al.
Publicado: (2020)

Toll-Like Receptor-Mediated Cardiac Injury during Experimental Sepsis
por: Lackner, Ina, et al.
Publicado: (2020)

The Prognostic Value of Troponin in Pediatric Polytrauma
por: Braun, Christian Karl, et al.
Publicado: (2019)

Hemorrhagic Shock Induces a Rapid Transcriptomic Shift of the Immune Balance in Leukocytes after Experimental Multiple Injury
por: Debler, Lisa, et al.
Publicado: (2021)

Laboratory Markers in the Management of Pediatric Polytrauma: Current Role and Areas of Future Research
por: Weber, Birte, et al.
Publicado: (2021)

Evaluation of the gut microbiome in association with biological signatures of inflammation in murine polytrauma and shock
por: Appiah, Sandra A., et al.
Publicado: (2021)

Role of Complement C5 in Experimental Blunt Chest Trauma-Induced Septic Acute Lung Injury (ALI)
por: Kalbitz, Miriam, et al.
Publicado: (2016)

Complement C5a Alters the Membrane Potential of Neutrophils during Hemorrhagic Shock
por: Messerer, David A. C., et al.
Publicado: (2018)

The Pathophysiology and Management of Hemorrhagic Shock in the Polytrauma Patient
por: Fecher, Alison, et al.
Publicado: (2021)

Alteration of complement hemolytic activity in different trauma and sepsis models
por: Ehrnthaller, Christian, et al.
Publicado: (2012)

Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients
por: Karasu, Ebru, et al.
Publicado: (2020)

Experimental blunt chest trauma-induced myocardial inflammation and alteration of gap-junction protein connexin 43
por: Kalbitz, Miriam, et al.
Publicado: (2017)

Inflammatory response of mesenchymal stromal cells after in vivo exposure with selected trauma-related factors and polytrauma serum
por: Amann, Elisa Maria, et al.
Publicado: (2019)

Mesenchymal Stem Cells after Polytrauma: Actor and Target
por: Huber-Lang, Markus, et al.
Publicado: (2016)

Neurochemical Monitoring of Traumatic Brain Injury by the Combined Analysis of Plasma Beta-Synuclein, NfL, and GFAP in Polytraumatized Patients
por: Halbgebauer, Rebecca, et al.
Publicado: (2022)

Polytrauma in the elderly: a review
por: Braun, Benedikt Johannes, et al.
Publicado: (2016)

Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction
por: Karasu, Ebru, et al.
Publicado: (2019)

Multifactorial Shock: A Neglected Situation in Polytrauma Patients
por: Luo, Jialiu, et al.
Publicado: (2022)

Fed State Prior to Hemorrhagic Shock and Polytrauma in a Porcine Model Results in Altered Liver Transcriptomic Response
por: Determan, Charles, et al.
Publicado: (2014)

Takotsubo Cardiomyopathy in a Polytrauma Patient With Subarachnoid Hemorrhage
por: Krishna, Mithun Murali, et al.
Publicado: (2023)

New Insights into the Role of Peroxisome Proliferator-Activated Receptors in Regulating the Inflammatory Response after Tissue Injury
por: Neher, Miriam D., et al.
Publicado: (2012)

Corrigendum: Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction
por: Karasu, Ebru, et al.
Publicado: (2019)

Lung injury after asphyxia and hemorrhagic shock in newborn piglets: Analysis of structural and inflammatory changes
por: Weber, Birte, et al.
Publicado: (2019)

Polytrauma
por: Guerado, Enrique
Publicado: (2015)

A Four-Compartment Metabolomics Analysis of the Liver, Muscle, Serum, and Urine Response to Polytrauma with Hemorrhagic Shock following Carbohydrate Prefeed
por: Witowski, Nancy, et al.
Publicado: (2015)

A porcine polytrauma model with two different degrees of hemorrhagic shock: outcome related to trauma within the first 48 h
por: Eschbach, D., et al.
Publicado: (2015)

Left ventricular function during porcine-resuscitated septic shock with pre-existing atherosclerosis
por: Nußbaum, Benedikt L., et al.
Publicado: (2016)

Systemic and Cardiac Alterations After Long Bone Fracture
por: Weber, Birte, et al.
Publicado: (2020)

Erratum to: Left ventricular function during porcine-resuscitated septic shock with pre-existing atherosclerosis
por: Nußbaum, Benedikt L., et al.
Publicado: (2016)

Molecular mechanisms of inflammation and tissue injury after major trauma-is complement the "bad guy"?
por: Neher, Miriam D, et al.
Publicado: (2011)

Trauma, a Matter of the Heart—Molecular Mechanism of Post-Traumatic Cardiac Dysfunction
por: Weber, Birte, et al.
Publicado: (2021)

Inflammatory Changes and Coagulopathy in Multiply Injured Patients
por: Huber-Lang, Markus, et al.
Publicado: (2015)

Impact of surface coating and systemic anticoagulants on hemostasis and inflammation in a human whole blood model
por: Spiegelburg, Doreen Tabea, et al.
Publicado: (2023)

Systemic Inflammatory Effects of Traumatic Brain Injury, Femur Fracture, and Shock: An Experimental Murine Polytrauma Model
por: Probst, C., et al.
Publicado: (2012)

Accuracy and outcome of rapid ultrasound in shock and hypotension (RUSH) in Egyptian polytrauma patients
por: Elbaih, Adel Hamed, et al.
Publicado: (2018)

Combined Heterozygous Genetic Variations in Complement C2 and C8B: An Explanation for Multidimensional Immune Imbalance?
por: Mannes, Marco, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_fohl8nllq50mpubrn8nedkp0r7