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Systemic effects in naïve mice injected with immunomodulatory lectin ArtinM
Toll-like receptors (TLR) contain N-glycans, which are important glycotargets for plant lectins, to induce immunomodulation. The lectin ArtinM obtained from Artocarpus heterophyllus interacts with TLR2 N-glycans to stimulate IL-12 production by antigen-presenting cells and to drive the immune respon...
Autores principales: | Oliveira Brito, Patrícia Kellen Martins, Gonçalves, Thiago Eleutério, Fernandes, Fabrício Freitas, Miguel, Camila Botelho, Rodrigues, Wellington Francisco, Lazo Chica, Javier Emílio, Roque-Barreira, Maria Cristina, da Silva, Thiago Aparecido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662225/ https://www.ncbi.nlm.nih.gov/pubmed/29084277 http://dx.doi.org/10.1371/journal.pone.0187151 |
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