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Unfolding the chaperone story

Protein folding in the cell was originally assumed to be a spontaneous process, based on Anfinsen’s discovery that purified proteins can fold on their own after removal from denaturant. Consequently cell biologists showed little interest in the protein folding process. This changed only in the mid a...

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Detalles Bibliográficos
Autor principal: Hartl, F. Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662250/
https://www.ncbi.nlm.nih.gov/pubmed/29084909
http://dx.doi.org/10.1091/mbc.E17-07-0480