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Rare case of pulmonary lymphomatoid granulomatosis in conjunction with tuberculosis: A case report
RATIONALE: Lymphomatoid granulomatosis is a very rare Epstein-Barr virus-driven lymphoproliferative disease. This disease has high mortality owing to its low incidence in conjunction with nonspecific presentations, which contribute to delays in diagnosis. PATIENT: An 87-year-old male had a week-long...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662409/ https://www.ncbi.nlm.nih.gov/pubmed/29049243 http://dx.doi.org/10.1097/MD.0000000000008323 |
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author | Ha, Young Woo Kim, Chul Hwan Park, Yong Sohn, Jang Wook Kim, Min Ja Yoon, Young Kyung |
author_facet | Ha, Young Woo Kim, Chul Hwan Park, Yong Sohn, Jang Wook Kim, Min Ja Yoon, Young Kyung |
author_sort | Ha, Young Woo |
collection | PubMed |
description | RATIONALE: Lymphomatoid granulomatosis is a very rare Epstein-Barr virus-driven lymphoproliferative disease. This disease has high mortality owing to its low incidence in conjunction with nonspecific presentations, which contribute to delays in diagnosis. PATIENT: An 87-year-old male had a week-long history of intermittent fever and general weakness. A chest radiograph showed multifocal patchy consolidations with nodular lesions. DIAGNOSES: Open lung biopsy using video-assisted thoracic surgery resulted in a diagnosis of grade III lymphomatoid granulomatosis. Three days after surgery, Mycobacterium tuberculosis complex was identified from the culture of sputum samples collected at admission. INTERVENTION AND OUTCOMES: Antituberculous treatment was commenced first. However, after 34 days of antituberculosis medication, the patient died owing to aggravated lymphomatoid granulomatosis. LESSONS: This case highlights the fact that rare diseases should also be considered in differential diagnosis, particularly with a common presentation such as multiple lung nodules. Furthermore, a diagnosis of pulmonary lymphomatoid granulomatosis was made after open lung biopsy. To our knowledge, this is the first case of lymphomatoid granulomatosis coexisting with active tuberculosis in the Republic of Korea, where tuberculosis is endemic. |
format | Online Article Text |
id | pubmed-5662409 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-56624092017-11-21 Rare case of pulmonary lymphomatoid granulomatosis in conjunction with tuberculosis: A case report Ha, Young Woo Kim, Chul Hwan Park, Yong Sohn, Jang Wook Kim, Min Ja Yoon, Young Kyung Medicine (Baltimore) 4900 RATIONALE: Lymphomatoid granulomatosis is a very rare Epstein-Barr virus-driven lymphoproliferative disease. This disease has high mortality owing to its low incidence in conjunction with nonspecific presentations, which contribute to delays in diagnosis. PATIENT: An 87-year-old male had a week-long history of intermittent fever and general weakness. A chest radiograph showed multifocal patchy consolidations with nodular lesions. DIAGNOSES: Open lung biopsy using video-assisted thoracic surgery resulted in a diagnosis of grade III lymphomatoid granulomatosis. Three days after surgery, Mycobacterium tuberculosis complex was identified from the culture of sputum samples collected at admission. INTERVENTION AND OUTCOMES: Antituberculous treatment was commenced first. However, after 34 days of antituberculosis medication, the patient died owing to aggravated lymphomatoid granulomatosis. LESSONS: This case highlights the fact that rare diseases should also be considered in differential diagnosis, particularly with a common presentation such as multiple lung nodules. Furthermore, a diagnosis of pulmonary lymphomatoid granulomatosis was made after open lung biopsy. To our knowledge, this is the first case of lymphomatoid granulomatosis coexisting with active tuberculosis in the Republic of Korea, where tuberculosis is endemic. Wolters Kluwer Health 2017-10-20 /pmc/articles/PMC5662409/ /pubmed/29049243 http://dx.doi.org/10.1097/MD.0000000000008323 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-nc-sa/4.0 |
spellingShingle | 4900 Ha, Young Woo Kim, Chul Hwan Park, Yong Sohn, Jang Wook Kim, Min Ja Yoon, Young Kyung Rare case of pulmonary lymphomatoid granulomatosis in conjunction with tuberculosis: A case report |
title | Rare case of pulmonary lymphomatoid granulomatosis in conjunction with tuberculosis: A case report |
title_full | Rare case of pulmonary lymphomatoid granulomatosis in conjunction with tuberculosis: A case report |
title_fullStr | Rare case of pulmonary lymphomatoid granulomatosis in conjunction with tuberculosis: A case report |
title_full_unstemmed | Rare case of pulmonary lymphomatoid granulomatosis in conjunction with tuberculosis: A case report |
title_short | Rare case of pulmonary lymphomatoid granulomatosis in conjunction with tuberculosis: A case report |
title_sort | rare case of pulmonary lymphomatoid granulomatosis in conjunction with tuberculosis: a case report |
topic | 4900 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662409/ https://www.ncbi.nlm.nih.gov/pubmed/29049243 http://dx.doi.org/10.1097/MD.0000000000008323 |
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