Transcriptome Analysis of Circulating Immune Cell Subsets Highlight the Role of Monocytes in Zaire Ebola Virus Makona Pathogenesis

Existing models of Ebola virus disease (EVD) suggest antigen-presenting cells are initial targets of Zaire ebolavirus (ZEBOV). In vitro studies have shown that ZEBOV infection of monocytes and macrophages results in the production of inflammatory mediators, which may cause lymphocyte apoptosis. Howe...

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Detalles Bibliográficos
Autores principales: Menicucci, Andrea R., Versteeg, Krista, Woolsey, Courtney, Mire, Chad E., Geisbert, Joan B., Cross, Robert W., Agans, Krystle N., Jankeel, Allen, Geisbert, Thomas W., Messaoudi, Ilhem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662559/
https://www.ncbi.nlm.nih.gov/pubmed/29123522
http://dx.doi.org/10.3389/fimmu.2017.01372

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