Heparan sulfate proteoglycans (HSPGs) and chondroitin sulfate proteoglycans (CSPGs) function as endocytic receptors for an internalizing anti-nucleic acid antibody

A subset of monoclonal anti-DNA autoantibodies enters a variety of living cells. Here, we aimed to identify the endocytic receptors recognized by an internalizing anti-nucleic acid autoantibody, the 3D8 single-chain variable fragment (scFv). We found that cell surface binding and internalization of...

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Detalles Bibliográficos
Autores principales: Park, Hyunjoon, Kim, Minjae, Kim, Hye-Jin, Lee, Yeonjin, Seo, Youngsil, Pham, Chuong D., Lee, Joungmin, Byun, Sung June, Kwon, Myung-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662561/
https://www.ncbi.nlm.nih.gov/pubmed/29085061
http://dx.doi.org/10.1038/s41598-017-14793-z

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