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Klotho Inhibits Interleukin-8 Secretion from Cystic Fibrosis Airway Epithelia

Chronic inflammation is a hallmark of cystic fibrosis (CF) and associated with increased production of transforming growth factor (TGF) β and interleukin (IL)-8. α-klotho (KL), a transmembrane or soluble protein, functions as a co-receptor for Fibroblast Growth Factor (FGF) 23, a known pro-inflammat...

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Detalles Bibliográficos
Autores principales:	Krick, Stefanie, Baumlin, Nathalie, Aller, Sheyla Paredes, Aguiar, Carolina, Grabner, Alexander, Sailland, Juliette, Mendes, Eliana, Schmid, Andreas, Qi, Lixin, David, Nicolae V., Geraghty, Patrick, King, Gwendalyn, Birket, Susan E., Rowe, Steven M., Faul, Christian, Salathe, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662572/ https://www.ncbi.nlm.nih.gov/pubmed/29085059 http://dx.doi.org/10.1038/s41598-017-14811-0

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