Phosphatidylinositol transfer protein-α in platelets is inconsequential for thrombosis yet is utilized for tumor metastasis

Platelets are increasingly recognized for their contributions to tumor metastasis. Here, we show that the phosphoinositide signaling modulated by phosphatidylinositol transfer protein type α (PITPα), a protein which shuttles phosphatidylinositol between organelles, is essential for platelet-mediated...

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Detalles Bibliográficos
Autores principales: Zhao, Liang, Thorsheim, Chelsea L., Suzuki, Aae, Stalker, Timothy J., Min, Sang H., Lian, Lurong, Fairn, Gregory D., Cockcroft, Shamshad, Durham, Amy, Krishnaswamy, Sriram, Abrams, Charles S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662573/
https://www.ncbi.nlm.nih.gov/pubmed/29084966
http://dx.doi.org/10.1038/s41467-017-01181-4

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