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Contact guidance persists under myosin inhibition due to the local alignment of adhesions and individual protrusions
Contact guidance—cell polarization by anisotropic substrate features—is integral to numerous physiological processes; however the complexities of its regulation are only beginning to be discovered. In particular, cells polarize to anisotropic features under non-muscle myosin II (MII) inhibition, des...
Autores principales: | Kubow, Kristopher E., Shuklis, Victoria D., Sales, Dominic J., Horwitz, A. Rick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662575/ https://www.ncbi.nlm.nih.gov/pubmed/29085052 http://dx.doi.org/10.1038/s41598-017-14745-7 |
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