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VGLUT2 Trafficking Is Differentially Regulated by Adaptor Proteins AP-1 and AP-3

Release of the major excitatory neurotransmitter glutamate by synaptic vesicle exocytosis depends on glutamate loading into synaptic vesicles by vesicular glutamate transporters (VGLUTs). The two principal isoforms, VGLUT1 and 2, exhibit a complementary pattern of expression in adult brain that broa...

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Detalles Bibliográficos
Autores principales: Li, Haiyan, Santos, Magda S., Park, Chihyung K., Dobry, Yuriy, Voglmaier, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662623/
https://www.ncbi.nlm.nih.gov/pubmed/29123471
http://dx.doi.org/10.3389/fncel.2017.00324