Cargando…
Biomechanical, ultrastructural, and electrophysiological characterization of the non-human primate experimental glaucoma model
Laser-induced experimental glaucoma (ExGl) in non-human primates (NHPs) is a common animal model for ocular drug development. While many features of human hypertensive glaucoma are replicated in this model, structural and functional changes in the unlasered portions of trabecular meshwork (TM) of la...
Autores principales: | Raghunathan, VijayKrishna, Eaton, J. Seth, Christian, Brian J., Morgan, Joshua T., Ver Hoeve, James N., Yang, Chen-Yuan Charlie, Gong, Haiyan, Rasmussen, Carol A., Miller, Paul E., Russell, Paul, Nork, T. Michael, Murphy, Christopher J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662689/ https://www.ncbi.nlm.nih.gov/pubmed/29085025 http://dx.doi.org/10.1038/s41598-017-14720-2 |
Ejemplares similares
-
Lysophosphatidic Acid and IL-6 Trans-signaling Interact via YAP/TAZ and STAT3 Signaling Pathways in Human Trabecular Meshwork Cells
por: Yemanyi, Felix, et al.
Publicado: (2020) -
Extracellular Matrix Stiffness and TGFβ2 Regulate YAP/TAZ Activity in Human Trabecular Meshwork Cells
por: Li, Haiyan, et al.
Publicado: (2022) -
ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load
por: Kasetti, Ramesh B., et al.
Publicado: (2020) -
Wnt Activation After Inhibition Restores Trabecular Meshwork Cells Toward a Normal Phenotype
por: Dhamodaran, Kamesh, et al.
Publicado: (2020) -
Dexamethasone and Glucocorticoid-Induced Matrix Temporally Modulate Key Integrins, Caveolins, Contractility, and Stiffness in Human Trabecular Meshwork Cells
por: Yemanyi, Felix, et al.
Publicado: (2020)