Cargando…

Reinstatement of memory representations for lifelike events over the course of a week

When we remember an event, the content of that memory is represented across the brain. Detailed memory retrieval is thought to involve the reinstatement of those representations. Functional MRI combined with representational similarity analyses (RSA) of spatial patterns of brain activity has reveale...

Descripción completa

Detalles Bibliográficos
Autores principales: Oedekoven, Christiane S. H., Keidel, James L., Berens, Sam C., Bird, Chris M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662713/
https://www.ncbi.nlm.nih.gov/pubmed/29084981
http://dx.doi.org/10.1038/s41598-017-13938-4
_version_ 1783274688508592128
author Oedekoven, Christiane S. H.
Keidel, James L.
Berens, Sam C.
Bird, Chris M.
author_facet Oedekoven, Christiane S. H.
Keidel, James L.
Berens, Sam C.
Bird, Chris M.
author_sort Oedekoven, Christiane S. H.
collection PubMed
description When we remember an event, the content of that memory is represented across the brain. Detailed memory retrieval is thought to involve the reinstatement of those representations. Functional MRI combined with representational similarity analyses (RSA) of spatial patterns of brain activity has revealed reinstatement of recently-experienced events throughout a core memory retrieval network. In the present study, participants were scanned while they watched, immediately retrieved and then retrieved after a week, 24 short videos. Following the delayed retrieval, they freely recalled all videos outside of the scanner. We observed widespread within- and between-subject reinstatement effects within a posterior midline core memory retrieval network during all phases of the experiment. Within precuneus, bilateral middle temporal gyrus and the left hippocampus, reinstatement effects between the retrieval phases correlated with memory performance. These findings extend previous studies that have only employed short retention periods or highly rehearsed materials, demonstrating that memory representations for unique events are reliably reinstated over longer timeframes that are meaningful in the context of real-world episodic memory.
format Online
Article
Text
id pubmed-5662713
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-56627132017-11-08 Reinstatement of memory representations for lifelike events over the course of a week Oedekoven, Christiane S. H. Keidel, James L. Berens, Sam C. Bird, Chris M. Sci Rep Article When we remember an event, the content of that memory is represented across the brain. Detailed memory retrieval is thought to involve the reinstatement of those representations. Functional MRI combined with representational similarity analyses (RSA) of spatial patterns of brain activity has revealed reinstatement of recently-experienced events throughout a core memory retrieval network. In the present study, participants were scanned while they watched, immediately retrieved and then retrieved after a week, 24 short videos. Following the delayed retrieval, they freely recalled all videos outside of the scanner. We observed widespread within- and between-subject reinstatement effects within a posterior midline core memory retrieval network during all phases of the experiment. Within precuneus, bilateral middle temporal gyrus and the left hippocampus, reinstatement effects between the retrieval phases correlated with memory performance. These findings extend previous studies that have only employed short retention periods or highly rehearsed materials, demonstrating that memory representations for unique events are reliably reinstated over longer timeframes that are meaningful in the context of real-world episodic memory. Nature Publishing Group UK 2017-10-30 /pmc/articles/PMC5662713/ /pubmed/29084981 http://dx.doi.org/10.1038/s41598-017-13938-4 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Oedekoven, Christiane S. H.
Keidel, James L.
Berens, Sam C.
Bird, Chris M.
Reinstatement of memory representations for lifelike events over the course of a week
title Reinstatement of memory representations for lifelike events over the course of a week
title_full Reinstatement of memory representations for lifelike events over the course of a week
title_fullStr Reinstatement of memory representations for lifelike events over the course of a week
title_full_unstemmed Reinstatement of memory representations for lifelike events over the course of a week
title_short Reinstatement of memory representations for lifelike events over the course of a week
title_sort reinstatement of memory representations for lifelike events over the course of a week
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662713/
https://www.ncbi.nlm.nih.gov/pubmed/29084981
http://dx.doi.org/10.1038/s41598-017-13938-4
work_keys_str_mv AT oedekovenchristianesh reinstatementofmemoryrepresentationsforlifelikeeventsoverthecourseofaweek
AT keideljamesl reinstatementofmemoryrepresentationsforlifelikeeventsoverthecourseofaweek
AT berenssamc reinstatementofmemoryrepresentationsforlifelikeeventsoverthecourseofaweek
AT birdchrism reinstatementofmemoryrepresentationsforlifelikeeventsoverthecourseofaweek