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Proton-solute coupling mechanism of the maltose transporter from Saccharomyces cerevisiae

Mal11 catalyzes proton-coupled maltose transport across the plasma membrane of Saccharomyces cerevisiae. We used structure-based design of mutants and a kinetic analysis of maltose transport to determine the energy coupling mechanism of transport. We find that wildtype Mal11 is extremely well couple...

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Detalles Bibliográficos
Autores principales: Henderson, Ryan, Poolman, Bert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662749/
https://www.ncbi.nlm.nih.gov/pubmed/29084970
http://dx.doi.org/10.1038/s41598-017-14438-1