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Proton-solute coupling mechanism of the maltose transporter from Saccharomyces cerevisiae
Mal11 catalyzes proton-coupled maltose transport across the plasma membrane of Saccharomyces cerevisiae. We used structure-based design of mutants and a kinetic analysis of maltose transport to determine the energy coupling mechanism of transport. We find that wildtype Mal11 is extremely well couple...
Autores principales: | Henderson, Ryan, Poolman, Bert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662749/ https://www.ncbi.nlm.nih.gov/pubmed/29084970 http://dx.doi.org/10.1038/s41598-017-14438-1 |
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