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Identify a Blood-Brain Barrier Penetrating Drug-TNB using Zebrafish Orthotopic Glioblastoma Xenograft Model

The blood–brain barrier (BBB) is necessary for maintaining brain homeostasis, but it also represents a major challenge for drug delivery to the brain tumors. A suitable in vivo Glioblastoma Multiforme (GBM) model is needed for efficient testing of BBB crossable pharmaceuticals. In this study, we fir...

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Detalles Bibliográficos
Autores principales:	Zeng, Anqi, Ye, Tinghong, Cao, Dan, Huang, Xi, Yang, Yu, Chen, Xiuli, Xie, Yongmei, Yao, Shaohua, Zhao, Chengjian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662771/ https://www.ncbi.nlm.nih.gov/pubmed/29085081 http://dx.doi.org/10.1038/s41598-017-14766-2

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